NHS-Activated Gold Nanoparticles

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Cytodiagnostics NHS-activated Gold Nanoparticle Conjugation Kits have been optimized for high efficiency one-step conjugation of proteins and other primary amine-containing ligands to gold nanoparticles.

The kits contains ready-to-use pre-made mixtures. No activation or manipulation of the gold nanoparticles is required prior to conjugation, which often results in poor performing conjugates. Simply mix your protein with the pre-activated NHS ester gold nanoparticles supplied in the kit to generate your conjugate. 

NHS-Activated Gold Nanoparticles Conjugation

The precisely engineered gold surface coat on our NHS ester-activated gold nanoparticles results in high conjugation efficiency and stable conjugates while minimizing non-specific binding in your assay.

Features & Benefits of NHS-Activated Gold Nanoparticles

  • Results in covalently bound ligand and more stable conjugate.
  • Fast and convenient one-step conjugation reaction with no pre-activation requirements.
  • Spacer between the gold nanoparticle surface and conjugated ligand minimizes effects on the tertiary protein structure, which can lead to poor performing conjugates, a common problem seen in conjugates prepared by passive adsorption.
  • Precisely engineering surface coating that reduces non-specific protein binding in biological assays.