WHY CHOOSE US?


If you are looking for a customized assay to meet your unique diagnostics needs or need assistance in optimizing an existing assay for improved sensitivity, accuracy, or reproducibility, our LFA development service may be just what you need. Our team of experienced scientists can help you develop and optimize LFA assays that are tailored to your specific diagnostics goals and sample types.

TYPES

BENEFITS

Rapid test optimization: Antibody-based sandwich/direct/ 
competitive lateral flow  

· Our team can perform all optimization of passive vs. covalent conjugates of your antibodies to determine which method is most suitable for your assay. 

· Buffers, membrane striping conditions etc. can be optimized to give you the best possible sensitivity with the lowest background. 

· Qualitative yes/no, semi-quantitative and quantitative (with band intensity reader) final assay formats available  

· Phase-based projects: 

· An initial prototype will be generated to check viability of the antibodies in an LF assay format. 

· Further optimization/assistance towards commercialization available in subsequent phases 

Rapid test optimization: 

Aptamer/ 
oligonucleotide-based lateral flow 

· Same services available as for antibody-based lateral flow, but with our unique aptamer knowledge and techniques 

· Services also available combining antibodies and aptamers as detection molecules 

Custom passive antibody/protein nanoparticle conjugation 

· Allow our team of experts to perform laborious pH and protein loading experiments for you. 

· We can determine which conditions yield the most stable and LF functional conjugate 

Custom covalent antibody/protein nanoparticle conjugation 

· Our team will determine which linking chemistry best suits your antibody/protein. 

· We can assess the conjugate for LF functionality and sensitivity 

Aptamer/ 
oligonucleotide nanoparticle conjugation 

· Our team can perform laborious salt aging methods for you along with modern OligoREADY, AptamerREADY and covalent methods. 

· We can create multiple variations to determine which best suits your end usage  


By leveraging years of experience in nanoparticle manufacturing and assay development we can reduce the time from project inception to a finished product.


Whether it is a smaller project or full-scale assay development project with the goal of launching a commercial product, Cytodiagnostics and Cytogroup are here to help. 

 

  Common service and project types:


  • Antibody conjugation and screening
  • Oligo and Aptamer conjugation, discovery and screening
  • New assay development
  • Transfer and optimization of existing proof-of-concept assay into a flow based rapid test setting.
  • Deposition of your gold conjugate on conjugate pads

If you are interested in our custom assay development services learn more from our affiliate Cytogroup.

Download: Lateral Flow Service Brochure

 
Phase 1
Phase 2
Phase 3
Phase 4
Confidentiality Agreements are signed. Ideas will be thoroughly assessed with complete literature reviews
Labelling of Nanoparticles with either antibodies, aptamers, or other molecules. Complete initial conjugate studies.
Transfer Assay onto a Lateral flow or Vertical Flow Device. Establish optimized conditions.
Testing of Assay with relevant samples containing target of interest.